R&D Scientist – Complix Diepenbeek

An exciting opportunity has arisen at Complix for an R&D Scientist to join our research team based in Diepenbeek.

Company description

Complix is a leading Belgian biotech company committed to the development of breakthrough therapies for treatment of important disease, such as cancer and autoimmunity. Our proprietary technology platform is based on Alphabodies, a novel protein scaffold that combines the benefits of antibodies, including high specificity and potency, with those of small molecules, such as cell penetration and high stability. We have developed Cell Penetrating Alphabodies (CPABs) that can address disease targets present in the cytosol or in the nucleus of human cells and that play an important role in disease processes, like in the development and progression of cancer, or in regulation of the immune response. CPABs act with great specificity and high affinity on targets that are considered “intractable” by currently available drug formats. As a pioneer in this emerging field, Complix aims to develop a diverse pipeline of first-in-class therapeutics with the potential to cure severe diseases with high unmet medical need.

Complix is led by an experienced management team with a track record of success in the biotech industry and is backed by a syndicate of experienced life sciences investors, through which it has raised over €35 million in equity capital to date.

Job Description

We are looking for a PhD scientist to join an established team tasked with the screening, characterization and understanding of the function of Alphabody drug candidates for various therapeutic applications, with a focus on oncology, immuno-oncology and autoimmunity. Specifically, the candidate will be responsible for the development and application of cellular and molecular biology assays and implementation of discovery strategies to identify promising lead compounds. We offer a fulltime permanent contract, competitive salary package and benefits (pension, meal vouchers and health insurance). The role would suit an enthusiastic and energetic PhD scientist looking forward to make the leap to an exciting company in the biotech industry.

Key tasks and responsibilities

  • To plan, design and supervise/execute molecular and cellular biology assays to assess the mechanism of action of Alphabodies
  • To identify and establish new techniques in the laboratory
  • To critically analyze and interpret experimental data, and relate them to published literature
  • To design data systems and record and document data accurately in these systems
  • To contribute to scientific discussions and translate project goals in design and optimization of experimental procedures
  • To summarize data in written reports and presentations

Qualifications and skills

  • PhD degree in Biology, Immunology or corresponding fields
  • Knowledge and excellent technical skills in cellular and molecular biology assays
  • Experience in immuno-oncology is a must
  • Experience in working with in vivo mice models is a plus
  • Ability to work independently
  • Excellent time management skills and flexibility to adapt to changes in project priorities
  • Goal oriented
  • Excellent communication skills, oral as well as written.
  • High level of proficiency in English, knowledge of Dutch is an advantage but not essential.
  • A true team player

Contact

If you are interested in joining an exciting and dynamic team, please contact: ann.beyaert@complix.com